How long do cold sores last? What is the treatment for cold sores, are there any home remedies, and what medications treat oral herpes? Google H opportunity forums. Cold sores will usually heal within two weeks without treatment. For additional pain relief, using anti-inflammatory drugs such as aspirin , ibuprofen Advil , or acetaminophen Tylenol may be beneficial. Acyclovir, mg orally three times a day for five days: Can cold sores be spread to other body areas? However, as there are still virus particles present throughout every phase of the cold sore outbreak the infected area is still considered to be contagious until the skin has completely healed. It is important to keep in mind that these topical anesthetics have a short duration of action, usually only lasting minutes. The current FDA-approved oral antiviral drugs used in the treatment of herpes simplex virus in adults are acyclovir, valacyclovir Valtrex , and famciclovir Famvir. Some people notice itching, tingling or other sensations before they see anything on their skin.
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